The variant of lissencephaly or pachygyria that Corey has is mild and does not relate to most of the lissencephaly information listed on the internet and that is why we have this website to let other parents in our situation know:
The mild variety of pachygyria has a full life expectancy.
The lissencephaly sites we found state the life expectancy is up to 20 years of age.
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I ran across this site with an actual picture of a pachygyria brain. It states it is fatal but I was told Corey's variant is not. A total of 13 brain malformations are included.
http://runzwithscissors.net/gallery/brains/pachygyria
http://www.neurology.org/cgi/content/abstract/01.wnl.0000183747.05269.2dv1
For description and resources:
http://www.memorialhermann.org/library/healthguide/en-us/illnessconditions/topic.asp?hwid=nord454
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Brain scans of Lissencephaly and information visit:
http://www.med.uc.edu/neurorad/webpage/cna.html
Discussion:
Lissencephaly is the most severe of the migrational anomalies. Affected individuals are profoundly mentally retarded and usually have severe seizure disorders. A global migrational abnormality is postulated, occurring between 11-26 weeks. The cortex is abnormally thickened and sulcation largely absent, with 2-4 instead of the normal 6 cell layers of cortex. Colpocephaly is usually present.
Types:
I-Miller-Deiker- assd with 17p-
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